Immune System Support: Strengthens white-blood-cell function to guard against illness
doi: 10.1016/s0016-5085(97)70004-0 44 LiBChenLSunHYangWHuJHeYet al
Pycnogenol s favorable impact on blood circulation was demonstrated in multiple ways, like the improvement of endothelial function or microcirculation in clinical RDP trials on cardiovascular health, chronic venous insufficiency, on skin and hair health, eye health and menopause (9, 11, 12, 2022, 2833, 4347)
Saunas and steam rooms can be safely used after 24 hours
Gastrointestinal effects: the main titration bottleneck Nausea, diarrhea, constipation, and vomiting run around 40 to 44% overall, dose-dependent in how many people report them but mild-dominant in severity: severe events stay at or below about 1.7% in any category even at the top dose. In the obesity program the by-dose rates run nausea 25/29/28%, diarrhea 19/21/23%, and vomiting 8/11/13% at 5/10/15 mg. They concentrate during escalation and ease with time on a held dose
