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Shoshan M., N

For example, higher levels of homocysteine mean that certain proteins important in cardiovascular disease and neurodegenerative diseases can end up with a homocysteine attached or incorporated into them.[ref] The process of post-translational protein modification happens all the time and in a number of different ways, including the addition of other amino acids, sugar molecules, or fatty acids

This is a second degradation pathway of Nrf2, which seems to be independent of Keap1

This anti-aging peptide is a powerful complex of glycine, histidine, and lysine bound to a copper ion (Cu), vital for cellular signaling and repair

Additionally, the peptide's proposed anti-inflammatory properties (via modulation of TNF- and IL-6 in adipose tissue) and potential stimulation of chondrocyte metabolism offered biological plausibility for OA treatment