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Additionally, a randomized, double-blind, placebo-controlled trial in 162 elderly people (70 years) with mild vitamin B 12 deficiency found that vitamin B 12 supplementation for 24 weeks, alone or in combination with folic acid, did not improve memory performance (117)

The mechanism of toxicity in HET-S/HET-s prion incompatibility

Walls, J., Sinclair, L., & Finlay, D

The theoretical maximum amount in solution is determined by the relative amounts of its pH-dependent unprotonated and protonated forms and follows the Henderson-Hasselbalch and precipitation-pH (pHp) models ( Figures 3 , and S4, S5, in Supplemental Information )

Female or male age-matched mice (712 weeks old) were used for all experiments (unless otherwise stated) and euthanasia was performed by cervical dislocation