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However, any application beyond research should be approached with caution

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In vitro studies suggest that exposure to TB-500 may support cell movement and structural coordination, and may also participate in signaling pathways linked to angiogenesis and modulation of inflammatory mediators

Activation of the pY397 autophosphorylation site of FAK promotes SRC binding, leading to the conformational activation of SRC, and, subsequently, a dual activated FAKSRC signalling complex (Mitra et al, 2005)

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