The beneficial gut microbe Akkermansia muciniphila, for example, stimulates the secretion of glucagon-like peptide-1 (GLP-1), which plays a crucial role in regulating glucose levels and metabolism, and numerous studies have linked low levels of the microbe to diabetes , insulin resistance, obesity, and metabolic syndrome
Research has examined NNMT inhibition and its downstream effects on cellular NAD+ salvage, methylation balance and adipocyte energy metabolism, with preclinical work exploring roles in lipid handling and metabolic regulation
Protein lipoylation: an evolutionarily conserved metabolic regulator of health and disease
Combinatorial lipid-nanosystem for dermal delivery of 5-fluorouracil and resveratrol against skin cancer: delineation of improved dermatokinetics and epidermal drug deposition enhancement analysis
Copper, Oxidative Stress, and Autism The Hidden Chemistry Behind Behavior Copper and zinc are essential trace minerals, but in autism their balance is often disturbed