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Clinical Response: Doctors might change the dose based on how well the patient is doing

Its mechanism NNMT inhibition leading to AMPK activation directly improves insulin sensitivity, as demonstrated in the 2021 Nature Metabolism study where treated mice showed reduced hepatic steatosis and improved glucose tolerance

The clinical program and Phase 2b failure Phase 1 and 2a trials were successful , the peptide was safe, without significant side effects, and showed a mild lipolytic signal

It does not interact with glucose metabolism