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The associated increase in C2 production helps regulate this transition by reducing acetyl-CoA concentrations, thus allowing glucose oxidation to progress

The obtained HT potential targets were visualised using Cytoscape 3.9.1 software (Fig

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The investigators conducted a multicenter, double-blind, placebo-controlled, active-controlled phase 3a trial (ClinicalTrials.gov ID: NCT05567796) evaluating the efficacy and safety of the combination of semaglutide and cagrilintide in adults without diabetes with a body-mass index (BMI) of greater than or equal to 30 or greater than or equal to 27 with at least one obesity-related complication

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