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With GSH depleted, the thyroid has little to call upon to help mitigate oxidative stress and shuttle out toxins

Journal reference: Li, T., Tian, Y., Zhong, Q., et al

As a precaution, consult your OB-GYN before using any active-ingredient skincare product during pregnancy or breastfeeding this applies to kojic acid, vitamin C serums, and retinoids alike

Recent evidence demonstrates that stimulation of the TSab on the TSH-R in the orbital fibroblasts can lead to a crosstalk of this receptor with the insulin growth factor 1 receptor (IGF-1R) which stimulates hyaluronan accumulation in the orbital muscles and transformation of orbital fibroblasts into adipocytes (283, 284)