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Description

Davies MJ

Knab et al., 2022

This chelation reaction can occur in both intra- and extra-cellular environments due to the lipophilic properties of dimercaprol, but it is most prominent within extracellular compartments

Wink S, Hiemstra S, Herpers B, van de Water B

Alternatively, oxidation and activation of GCL may not require additional molecular systems, but may occur by direct interaction with glutathione to mediate redox changes that modulate activity