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10.1371/journal.pone.0082334 141

This helps maintain receptor sensitivity and ensures long-term effectiveness

Introduce it gradually every other day at first to gauge tolerance

JBRA Assist Reprod 2013;17:152157

In GBM, the metabolic profiling of GBM cell lines showed that the abundance of GTP nucleotides correlates with resistance to radiation therapy, while inhibition of GTP synthesis sensitized GBM cells to irradiation by impairing DNA repair [84]