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Abstract Advanced maternal age is a key factor in female infertility, primarily due to declines in ovarian reserve and oocyte quality

For the outcome of function, a negative SMD indicates improved function following the intervention

Although both resolved and sensitized bladders have enhanced early Cox-2 responses in vivo, by 24 h post-infection, the bladder inflammatory response is only sustained in sensitized mice 7 and Cox-2 inhibition protects sensitized mice against severe recurrent cystitis 6,8