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A reciprocal activation loop exists between microglia and T cells (Xu et al., 2023): M1-polarized microglia secrete IL-6 and IL-1 which, in the presence of transforming growth factor-, promote Th17 differentiation while inhibiting Treg development in nave T cells (Zhang C

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10.1038/s41392-021-00658-5 209 ZhaoY.YeX.XiongZ.IhsanA.AresI.MartnezM.et al (2023)