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Patients should be counseled that sustainable weight management requires long-term commitment to lifestyle changes, and medication is an adjunct rather than a replacement for healthy behaviors

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Such glutathionylation has been implicated as a mechanism in protection against the irreversible protein oxidation during oxidative stress [69]

Since the myelin sheath that protects nerve cells is in continual flux the methylmalonyl-CoA-induced inhibition of fatty acid synthesis results in the eventual destruction of the sheath

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