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As a final test for the physiological significance of the 6-AH family blockade of Met-dependent cellular outcomes, we evaluated the ability of D-Nle-Cys-Ile-NH(CH 2 ) 5 CONH 2 to inhibit the formation of pulmonary colonies by B16-F10 cells after tail vein injection in mice

These figures are derived from preclinical (rodent) reference work, not from any approved human dosing

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