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Malabsorption Malabsorption of B12 is prevalent in people with gastrointestinal (GI) disorders and GI surgeries

B12 is important because it is needed to make DNA, or the genetic material that makes up all your cells

Conversely, medications that further slow gastric emptying, such as anticholinergics or opioid analgesics, may exacerbate gastrointestinal adverse effects including nausea, vomiting, and constipation

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This can include slight redness, swelling, or sensitivity around the site