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With a half-life of ~30 minutes it produces pulsatile GH release mimicking natural GH secretion rhythms making it the preferred GHRH analog for physiologically accurate GH pulse research

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As we anticipated, both male and female CR-fed 3xTg mice have a distinct RER curve from AL and DL-fed mice, reflecting the rapid induction of lipogenesis following feeding and a subsequent switch to utilizing lipids as the primary energy source (Fig

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3d) when transferred into germ-free (GF) mice