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A deficiency in B12 can disrupt this process, leading to anemia, impaired red blood cell production and even nerve damage[7]

When reactive oxygen species threaten your cells, glutathione steps in and neutralizes them, helping to manage oxidative stress

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This can cause some individual hairs to turn white or gray

Additionally, conditions such as severe cardiac or pulmonary insufficiency that lead to reduced peripheral perfusion, lactic acidosis, liver disease, alcohol dependence, or the use of intramuscular contrast agents for radiographic imaging also represent exclusion criteria due to the increased risk of adverse effects, particularly lactic acidosis (80, 121)