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(1992) Heterogeneity of carboxylesterases in rat liver cells Biochem

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Functional complementation of anthocyanin sequestration in the vacuole by widely divergent glutathione S -transferases

In his foundational report with Thaler, a tripeptide purified from human serum was shown to prolong the survival of cultured normal liver cells while also stimulating growth in neoplastic (hepatoma) liver cells an early hint both of the molecules regenerative signaling and of the fact that its growth-modulating activity is context-dependent rather than uniformly benign

However, while these benefits are enticing, they must be weighed against potential risks, especially for those with existing kidney concerns