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M.ChoudharyM.ChowdhuryR.SinghviG

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Mitochondrial respiratory chain complexes I (NADH-CoQ reductase complex), II (succinate dehydrogenase complex), III (cytochrome bc-1 complex) can, under different metabolic stress, produce ROS that damage the mitochondrial membrane, resulting in lipid peroxidation and ultimately leading to ferroptosis

Miscommunication, routine-based decision-making, and overlooked hazards are common contributors