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Schoenenberger collected blood from the cerebral veins of electrically sleep-induced rabbits and isolated a small peptide that, when infused into waking rabbits, appeared to increase slow-wave (delta) EEG activity

It increases the risk for multiple metabolic complications including type 2 diabetes (T2D), metabolic-dysfunction associated steatotic liver disease (MASLD, previously known as non-alcoholic fatty liver disease), cardiovascular disease as well as many mechanical complications such as osteoarthritis and obstructive sleep apnoea (OSA) [3]

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