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Co-expression of urotensin II and its receptor (GPR14) in human cardiovascular and renal tissues

However, in several cases the sulfonation reaction can lead to formation of a more active metabolite compared to the parent compound as is the case for the hair follicle stimulant minoxidil (Buhl et al., 1990) or the diuretic agent triamterene (Mutschler et al., 1983)

Interestingly, Se deficiency is associated with pro-longevity mechanisms because of reduced amino acid levels and altered nutrient signaling

Elevated concentrations of metals (such as As, Cd, Cr, Hg, Ni, and Pb) may affect photosynthetic apparatus, electron transport chain and chlorophyll biosynthesis, induce cellular damage, impair cellular redox homeostasis, and finally cause cellular metabolic arrest (Anjum et al., 2012

Cerqueira et al., 2020)