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You may need to get B12 shots on a regular basis to keep your levels up and feeling great

Patients experiencing significant nausea may benefit from: Evening administration : Some patients find injecting before bedtime allows them to sleep through periods of nausea, though the timing of symptoms varies by product and individual

Research from the NCBI explains that those with severe deficiencies or trouble absorbing B12 might need regular doses to keep their levels steady

Sa1100 randomized open label trial comparing efficacy of oral versus intramuscular vitamin B12 supplementation for treatment of vitamin B12 deficiency