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Combining siramesine and lapatinib causes ferroptosis through iron transport disruption leading to increased ROS in breast cancer [182, 183], or targeting GPX4 might be a potential strategy to enhance antitumor effects of lapatinib in NSCLC cells [184]

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Yet, folate status is considered inadequate in a majority of women of childbearing age worldwide

A curated and standardized adverse drug event resource to accelerate drug safety research