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Serious adverse effects are uncommon but possible, including allergic reactions, severe injection site reactions if improper technique is used, and excessive detoxification responses in susceptible individuals

This may lead to subsequent physiological abnormalities including gut dysbiosis and systemic inflammation, eventually resulting in a pathological clotting system, chronic endothelialitis, vasoconstriction, and hypoxia, as found in similar conditions such as heat stroke (183)

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Thus, further research on herbal medicine use during pregnancy is highly warranted in sub-Saharan Africa, as it might prevent maternal mortality and morbidity and decrease the possibility of endangering the health of fetuses

Fibromyalgia is frequently treated as a purely pain-based condition