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J Cell Biochem 104:13561363 Kawanishi N, Sugimoto T, Shibata J, Nakamura K, Masutani K, Ikuta M, Hirai H (2006) Structure-based drug design of a highly potent CDK1, 2, 4, 6 inhibitor with novel macrocyclic quinoxalin-2-one structure

The blame almost certainly lies with other hormonally active agents used concurrently or, just as critically, with contaminated, low-purity products from untrustworthy suppliers

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