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Typical Post-Injection Timeline First 24-48 hours: Mild to moderate pain at the injection site Localized warmth and redness Slight swelling around the knee Temporary stiffness or reduced range of motion Days 2-3: Gradual reduction in swelling Decreased pain and tenderness Return to normal mobility Possible spongy sensation when walking [4] The American Academy of Orthopaedic Surgeons notes that patients should avoid excessive activity, such as jogging or heavy lifting for the first 48 hours after injection [2]

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For HPLC statistical analyses, data are expressed as means SEM and the total glutathione-MP conjugate was compared with the non-enzymatic conjugate using the Students t-test

By utilizing the Joule-Thompson effect, the CO2 expands and rapidly cools to -78C as it exits the catheter

This language, used consistently in published study reports, indicates that researchers specifically looked for problems and didn't find them