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It was initially planned to recruit 20 analyzable patients (who completed the two-treatment periods) to have 80% power to detect, with a two-sided test at 0.05 significance level, an absolute decrease in percentage over total target of 10% under the A-dopamine period compared with the control (oral l-dopa-alone treatment) period, by assuming a standard deviation of 15% and a within-patient correlation of 0.5 to account for the crossover design

Gene expression of renal cells in kidney organoids, such as podocytes and tubular epithelial cells, was increased after ERT in GLA-KO human iPSC kidney organoids (Fig

Taranta A, Bellomo F, Petrini S, Polishchuk E, De Leo E, Rega LR, Pastore A, Polishchuk R, De Matteis MA, Emma F (2017) Cystinosin-LKG rescues cystine accumulation and decreases apoptosis rate in cystinotic proximal tubular epithelial cells

Cellular Signal 40:99115

It is made up of three amino acids : glutamine glycine cysteine What are its main functions