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Animal models showed that verapamil accelerated bactericidal activity and achieved durable sterilization in infected mice [86]

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Mechanistically, Legumain mediates the chaperone-mediated autophagy of GPX4 via HSP90/HSC70, decreasing GPX4 abundance and promoting AKI-associated ferroptosis ( in vitro I/R model alleviated ferroptosis by regulating the GSHGPX4 pathway ( /GSHGPX4 axis as a critical therapeutic node in renal I/R injury: interventions targeting pathway-related genes or enhancing key protein levels boost renal antioxidant capacity, offering novel strategies to mitigate I/R-induced kidney damage

Fortunately, a fluttering heartbeat that's infrequent or short-lived is often harmless and goes away on its own

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