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Also, researchers found that silymarin could entirely prevent injury to renal cells incubated with elevated glucose concentrations while blocking production of oxidative stress markers (Wenzel 1996)

Hattangadi SM et al

Inhibition of autophagy in cells under high-fat conditions aggravates atherosclerosis, and iron accumulation often occurs in plaques, which may be caused by dysregulated mitophagy and the abrogation of the fragile metabolic balance in foam cells [225, 226]

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