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If you have a thyroid condition and/or any of the risk factors of B12 deficiency as outlined above, there is a very good chance that you are not properly absorbing B12, even if you eat a diet rich in animal proteins, so it is important to get tested if you suspect a deficiency

Switching to sterile water for reconstitution eliminates preservative reactions but reduces shelf life to 7 days maximum

This is typical with any subcutaneous injection and usually resolves within an hour

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Category 3 preparations are produced in ISO-classified cleanroom environments with extensive environmental monitoring, personnel qualification, and process validation