Conversion ratio of tryptophan to niacin in Japanese women fed a purified diet conforming to the Japanese Dietary Reference Intakes
The study showed significant increases in intracellular glutathione levels after just 2 weeks of use, as well as demonstrating its ability to support healthy NK cell function and oxidative stress levels.* Key insights: Bolsters Antioxidant Action* Glutathione is a tri-peptide composed of the three amino acids L-glutamic acid, L-cysteine, and L-glycine
ARA-290 received FDA Orphan Drug Designation for this indication TRPV1-mediated pain models ARA-290 demonstrated specific inhibition of TRPV1 channel activity, relieving capsaicin-induced mechanical hypersensitivity in pre-clinical nociceptor models Complex Regional Pain Syndrome (CRPS) investigational studies have examined ARA-290 in CRPS models due to its dual anti-inflammatory and nociceptor-targeting mechanism Chronic neuropathic pain multiple studies confirm ARA-290 reduces neuroinflammation in the spinal cord by suppressing TNF-, IL-1, and other pro-inflammatory cytokines that maintain chronic pain states Neuroprotection and CNS Research: Cerebral ischaemia/stroke models Wang et al
Continuous, but not intermittent, regimens of hypoxia prevent and reverse ataxia in a murine model of Friedreichs ataxia
The ScienCell GPx Assay provides an indirect method to quantify the activity of total glutathione peroxidase
