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PCBs (polychlorinated biphenyls, industrial chemicals now banned but still present in the environment), DDT/DDE (a legacy pesticide and its primary breakdown product), and PBDEs (polybrominated diphenyl ethers, used as flame retardants) concentrate in animal fat and accumulate further up the food chain

Sun et al., 2009), and the remaining structure reveals a unique long-distance electrostatic interaction between the active-site cysteine persulfide anion and the positively charged carbonyl carbon of the inhibitor (3MSTI3MT-3) ( O -alkyl and oxamic hydrazone complexes, AOAA, PAG and oxamic hydrazide are likely to inhibit their target enzymes in an irreversible manner

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