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gene expression modulation (~31% of human genes per Connectivity Map analysis)

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Male C57BL/6 mice (68 weeks old) were randomly divided into different subgroups and anesthetized with 1.53% isoflurane, and a left abdominal incision was made to expose the pancreas

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414 A recent review of the evidence found that most studies examining subjective cognitive decline as an outcome showed higher prevalence among SGM older adults, while those examining objective measures of cognitive performance showed more mixed results