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While glucagon normally raises blood sugar, in this context it also stimulates energy use and fat metabolism, which researchers believe may contribute to the greater weight loss seen in clinical trials so far

Mean weight reductions from baseline at week 26 were dose-dependent for Cagrilintide

GH deficiency support FDA-approved as somatropin for growth hormone deficiency in children and adults one of its established clinical indications

No adverse events were reported in either study, but the small number of participants makes it difficult to draw broader conclusions

Otherwise, the safety profile appears favorable across most populations