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Perilymph (5 l) was then collected using a microcapillary inserted into the cochlear scala tympani

Why receptor subtype work matters for interpretation A common question is which receptor subtype is doing the work. A 2025 mechanistic study investigated AMY receptor subtype dependence and reported that cagrilintides body weight lowering effects depended on AMY1R and AMY3R in their models, which provides a more concrete receptor anchored explanation than general appetite language

The 3HA coding sequence was inserted in between the homology arms by overlapping extension

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Fang et al