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In osteoarthritis, the HA in synovial fluid decreases or changes over time

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Peptide hormones interact with receptor sites located on the cell surface and initiate a signal transduction cascade which is ultimately responsible for altering gene expression and cell behavior

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Following treatment with varying concentrations of BPC 157 and 24 hours of incubation, the cells were administered 0.1 ug/mL of growth hormone and incubated for an additional 24 hours in order to accurately measure cell viability by MTT assay