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The multi-pathway neurotrophic support reduces infarct volume, limits secondary neuronal loss, and improves functional recovery scores in MCAO (middle cerebral artery occlusion) models with effect sizes reaching 0.60.8 compared to vehicle controls

The properties of some potential neuroprotective regulatory peptides are listed in Table 1

For confirmed B12 deficiency without neurological involvement , the standard regimen comprises 1 mg hydroxocobalamin intramuscularly three times weekly for two weeks, followed by maintenance doses every two to three months for those with irreversible causes like pernicious anaemia

Therapeutic Potential BPC-157 is modified for greater stability than its parent compound and is shown to have systemic effects without the need for a carrier agent

10.1007/s12016-021-08899-6 Clin Rev Allergy Immunol