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J Transl Med (2011) 9:81

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The highest binding affinity for GPx4 with a docking score of 7.6kcal/mol and greater ligand exposure was exhibited by Lapatinib, which bonded with the enzyme at ASP165 and TYR169 residues

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The peptide appears to enhance stress adaptation capacity by modulating corticotropin-releasing hormone (CRH) and ACTH secretion patterns, potentially reducing the physiological toll of chronic stress on organ systems