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Investigators are particularly interested in determining the mechanisms by which effects observed in murine models relate to broader mammalian metabolic regulation, and whether different experimental conditions (young vs aged models, healthy vs metabolically compromised states) show differential responses to NNMT inhibition
Cavalcanti GS, Carvalho KC, Ferreira CDS, Chedraui P, Monteleone PAA, Baracat EC, et al