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The gradual breakdown of extracellular matrix (ECM) is a hallmark of KOA (Loeser, 2017), which is caused by an imbalance of catabolic and anabolic signals in cartilage

Dysbiosis and "leaky gut" are heavily correlated with migraine frequency [7]

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Zelda: I suppose the main thing is making sure, from a female perspective, if youre in perimenopause, making sure that those hormones are balanced

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