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3 Children absorb lead up to 8-times more efficiently than adults

The extracellular thiol/disulfide red-ox environment (determined by the interconversion between cysteine and cystine) is able to modulate cell proliferation, apoptosis, cell adhesion molecules, and proinflammatory signaling

These limitations hinder the reliability and applicability of pooled effect estimates and make it difficult to issue strong clinical recommendations for or against TCM use of TCM for tinnitus