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Doxorubicin (50, 37.5, 25, 12.5 and 10 M) was injected into the media 16 minutes into the experiment (between measurements 1 and 2), yielding concentration-dependent oxygen consumption profiles in a cell-free environment

10.1021/js980086i 156 ZhangY.BonzoJ

And they have no known pharmacological interactions

The third pathway is proline utilisation which occurs in mitochondria where proline is oxidised to pyrroline-5-carboxylate by mitochondrial proline dehydrogenase ( PUT1 ) which, in turn, is further oxidised to glutamate by 1-pyrroline-5-caboxylate dehydrogenase ( PUT2 ) 19

Protocol duration varies, but for a chronic condition like plantar fasciitis, research cycles often last from 4 to 8 weeks, and sometimes longer