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An early study by Jackson and Halestrap (130) documented lactate-induced intracellular acidification in rat hepatocytes, whereas Bozzo et al (131) observed only modest pH reductions following 5 mM lactate treatment in mouse neurons

Some of the preclinical research has included preliminary results for: Inflammatory bowel disease: In mouse studies, KPV reduced inflammation and protected the gut barrier

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Some studies found that certain B vitamins may help prevent some types of cancer, while others found evidence that high levels of B vitamins might cause some types of cancers

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