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Deficiency in one or more HPRs increases the level of most photorespiratory intermediates, including glycolate, glycine, serine, hydroxypyruvate and glycerate, and these metabolic phenotypes are affected by photoperiods 16,17,22

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It can be done as early as 10 years old, but it is best to wait until after puberty

UV spectrophotometry is used due to its precise, robust and minimum solvent consumption making it suitable for analysis of the drugs

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