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400 Conditional activation of autophagy under stress-responsive conditions is another emerging approach

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Understanding these factors is useful for patients who may be considering participation in a trial or who wish to discuss emerging therapies with their healthcare provider

Moreover, glial cells such as microglia and astrocytes play a dual role in buffering iron: while they can sequester iron released from dying neurons, their own ferroptosis may exacerbate inflammation and oxidative stress

The decrease in catalase activity suggests impaired antioxidant defence, which may be linked to epigenetic changes, including miRNA modulation, driven by the E6 oncoprotein [43]