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Their hydrophilicity prevents efficient transcellular transport (crossing through cell membranes), while their size prevents efficient paracellular transport (passing between cells)

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Burman RJ, Rosch RE, Wilmshurst JM, Sen A, Ramantani G, Akerman CJ, et al

Glutathione reduced form (GSH) is the active state of glutathione, which effectively neutralizes free radicals and maintains glutathione levels balance in the body

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