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10.1016/j.expneurol.2011.09.001 Exp Neurol

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It occurs naturally in the cells of plants, animals, and humans

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In the same AIA rabbit model, it was found that the parathyroid hormone related protein (PTHrP) was detected in diseased cartilage chondrocytes, suggesting that it has a role in this pathological condition, with a decrease in cell and matrix PTHrP in late AIA in parallel with the loss of chondrocytes, as happens in human RA cartilage (106)