Primary research applications include Alzheimer's disease, vascular dementia, age-related cognitive decline, and neurological recovery after brain injury
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GH levels decline approximately 14% per decade after age 30, and this decline contributes to loss of lean mass, increased body fat, reduced bone density, impaired recovery, and diminished skin quality
Moreover, the treatment should be able to reach the central nervous system, which is a difficulty for both drugs (must cross the bloodbrain barrier or be administered intrathecally) [263] and devices (surgical access to the CNS might be required)
Being the disorder chronic and persistent, the best achievable result is the stabilization of the disease