At pathological level, ROS becomes highly reactive, causing substantial damage to various cellular biomolecules such as nucleic acids, proteins and lipids (41)
Data Handing and Statistical Analysis Quantification of neutrophils and mast cells number in the digits and knees synovial tissue was performed with the image analysis system (AxioVision Software, Zeiss) (analyzing at least five distinct sections per mouse)
In the absence of a unified conceptual framework, distinctions between neuroprotection, symptomatic treatment, and disease modification often become obscured, risking the conflation of mechanistic plausibility with demonstrable clinical benefit
Chen H, Chen F, Hu F, Li Y, Zhang M, Zhou Q, et al
6, Tnf- , Il-6 , Il-1 , Il-1 , Il-17 , Il-22 , and Il-23 was significantly decreased in the IMQ-Fer-1 group compared to those of the IMQ group (Fig