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Tofacitinib also significantly inhibits IL-22-induced CXCL1 and CXCL5 expression in human colonic tissues, suggesting that targeting the IL-22/CXC chemokine axis through JAK/STAT inhibition may be a viable therapeutic strategy

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PMID: 10424526 20

IL-37 is increased in brains of children with autism spectrum disorder and inhibits human microglia stimulated by neurotensin (2019) Researchers studied the brains of eight children with autism and eight children without the disorder